Para Chloro Acetanilide G.R

Para Chloro Acetanilide (CAS No. 539-03-7) is an organic compound with the chemical formula C8H8ClNO. It is a derivative of acetanilide, where a chlorine atom is substituted at the para position of the benzene ring. This compound is widely used in the chemical and pharmaceutical industries due to its versatile properties and applications. Below is a detailed overview of its uses, properties, and significance.

Chemical Properties

Para Chloro Acetanilide is a white crystalline solid with a molecular weight of 169.61 g/mol. It is sparingly soluble in water but dissolves well in organic solvents like ethanol, acetone, and ether. The presence of the chlorine atom at the para position enhances its reactivity, making it a valuable intermediate in organic synthesis.

Uses of Para Chloro Acetanilide

1. Pharmaceutical Intermediate:
   • Para Chloro Acetanilide is primarily used as an intermediate in the synthesis of various pharmaceutical compounds. It serves as a building block for the production of drugs, including analgesics, antipyretics, and anti-inflammatory medications.
   • For example, it is used in the synthesis of paracetamol (acetaminophen), a widely used pain reliever and fever reducer.
2. Dye and Pigment Industry:
   • The compound is used in the manufacture of dyes and pigments. Its chemical structure allows it to act as a precursor for synthesizing azo dyes, which are commonly used in textiles, printing, and coloring industries.
3. Agrochemicals:
   • Para Chloro Acetanilide is utilized in the production of herbicides and pesticides. Its derivatives are effective in controlling weeds and pests in agricultural fields.
4. Chemical Research:
   • It is used as a reagent in organic synthesis and chemical research. Its reactivity makes it a valuable compound for studying substitution reactions and other chemical processes.
5. Rubber and Polymer Industry:
   • The compound is sometimes used as an additive in the rubber and polymer industries to improve the properties of materials, such as elasticity and durability.

Safety and Handling

Para Chloro Acetanilide is generally considered safe when handled properly, but it requires careful handling due to its chemical nature. Key safety considerations include:

• Toxicity: It may cause irritation to the skin, eyes, and respiratory system upon direct contact or inhalation.
• Environmental Impact: Proper disposal methods must be followed to prevent environmental contamination.
• Storage: It should be stored in a cool, dry place, away from direct sunlight and incompatible materials.

Personal protective equipment (PPE), such as gloves, goggles, and lab coats, should be worn when handling this compound. In case of accidental exposure, affected areas should be rinsed thoroughly with water, and medical attention should be sought if necessary.

Regulatory Status

Para Chloro Acetanilide is regulated under various chemical safety guidelines to ensure its safe use in industrial and laboratory settings. Manufacturers and users must comply with local and international regulations, such as REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals) in the European Union.

Conclusion

Para Chloro Acetanilide (CAS No. 539-03-7) is a versatile chemical compound with significant applications in the pharmaceutical, dye, agrochemical, and chemical industries. Its role as an intermediate in the synthesis of drugs and other chemicals highlights its importance in modern industrial processes. However, proper safety measures must be followed to ensure its safe handling and use. As with any chemical compound, understanding its properties and applications is essential for maximizing its benefits while minimizing risks.